Animal Viruses: Pathogenesis, Immune Escape, Spatio-Temporal Evolution, Vaccines, and Cross-Species Transmission

Viruses are everywhere in the environment, especially animal viruses. Not only do they cause serious economic damage (e.g. Newcastle disease virus and foot-and-mouth disease virus), but they can also spread to humans through different routes (e.g. Rabies and influenza viruses). According to statistics, more than 70% of the pathogens of human infectious diseases come from animals. Animal viruses not only affect animal health but also threaten human health to a certain extent. Research into the pathogenicity, immune escape, vaccines, transmission characteristics, and cross-species transmission of animal viruses carried by domestic or wild animals that may be in close contact with humans is critical for the prevention and control of emerging infectious diseases.

The imbalance of the human-animal-environment interface may favor the occurrence and the spread of animal foodborne and zoonotic diseases. Therefore, based on the one health, the mechanism of antimicrobial resistance, pathogenesis, and immune escape of pathogenic microorganisms isolated from animals and the environment are clarified, providing a new way to solve their impact on human health from the source.

In this Research Topic, we aim to elucidate the pathogenic mechanism, immune escape mechanism, spatial transmission, and cross-species transmission of viruses isolated from animals. Our goal is to provide new solutions for virus prevention and control.
We welcome submissions of Original Research, Reviews, and Mini-Review articles, focusing on cutting-edge research on animal viruses. Subtopics focusing on animal viruses include but are not limited to:
1) Interspecific transmission mechanisms
2) Spatial transmission characteristics
3) Pathogenic mechanisms
4) Immune escape mechanisms
5) Novel vaccine research
6) Human and/or veterinary clinical trials using vaccines against diseases (e.g. virus/cancer, etc.)
7) Immunotherapy for animal virus infection

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Posted on

November 30, 2019